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Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis
Caspase-1 is activated by a variety of stimuli after the assembly of the “inflammasome,” an activating platform made up of a complex of the NOD-LRR family of proteins. Caspase-1 is required for the secretion of proinflammatory cytokines, such as interleukin (IL)-1β and IL-18, and is involved in the...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118315/ https://ncbi.nlm.nih.gov/pubmed/16717117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060206 |
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