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Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

Collagens are the most abundant proteins in the human body, important in maintenance of tissue structure and hemostasis. Here we report that collagens are high affinity ligands for the broadly expressed inhibitory leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1). The interaction is depen...

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Detalhes bibliográficos
Main Authors: Lebbink, Robert Jan, de Ruiter, Talitha, Adelmeijer, Jelle, Brenkman, Arjan B., van Helvoort, Joop M., Koch, Manuel, Farndale, Richard W., Lisman, Ton, Sonnenberg, Arnoud, Lenting, Peter J., Meyaard, Linde
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118306/
https://ncbi.nlm.nih.gov/pubmed/16754721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052554
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