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IL-7 promotes T cell proliferation through destabilization of p27(Kip1)
Interleukin (IL)-7 is required for survival and homeostatic proliferation of T lymphocytes. The survival effect of IL-7 is primarily through regulation of Bcl-2 family members; however, the proliferative mechanism is unclear. It has not been determined whether the IL-7 receptor actually delivers a p...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118250/ https://ncbi.nlm.nih.gov/pubmed/16492801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051520 |
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