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Impaired response to Listeria in H2-M3–deficient mice reveals a nonredundant role of MHC class Ib–specific T cells in host defense

The major histocompatibility complex (MHC) class Ib molecule H2-M3 primes the rapid expansion of CD8(+) T cells by presenting N-formylated bacterial peptides. However, the significance of H2-M3–restricted T cells in host defense against bacteria is unclear. We generated H2-M3–deficient mice to inves...

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Detalhes bibliográficos
Main Authors: Xu, Honglin, Chun, Taehoon, Choi, Hak-Jong, Wang, Bin, Wang, Chyung-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118219/
https://ncbi.nlm.nih.gov/pubmed/16476767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051866
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