CCR5-dependent homing of naturally occurring CD4(+) regulatory T cells to sites of Leishmania major infection favors pathogen persistence

Pathogen persistence after clinical cure is a hallmark of many chronic infections. Previously, we showed that naturally occurring CD4(+)CD25(+) regulatory T (nTreg) cells rapidly accumulate within chronic dermal sites of Leishmania major infection where they suppress anti-pathogen CD4(+) T cell resp...

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Bibliographic Details
Main Authors: Yurchenko, Ekaterina, Tritt, Michael, Hay, Valerie, Shevach, Ethan M., Belkaid, Yasmine, Piccirillo, Ciriaco A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118140/
https://ncbi.nlm.nih.gov/pubmed/17015634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060956
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