Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection

Numerous microbes establish persistent infections, accompanied by antigen-specific CD8 T cell activation. Pathogen-specific T cells in chronically infected hosts are often phenotypically and functionally variable, as well as distinct from T cells responding to nonpersistent infections; this phenotyp...

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Detalhes bibliográficos
Main Authors: Vezys, Vaiva, Masopust, David, Kemball, Christopher C., Barber, Daniel L., O'Mara, Leigh A., Larsen, Christian P., Pearson, Thomas C., Ahmed, Rafi, Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118117/
https://ncbi.nlm.nih.gov/pubmed/16966427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060995
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