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Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson's disease
OBJECTIVE: The safety and tolerability of adjunctive tolcapone initiated simultaneously with levodopa was evaluated with a focus on increases in liver transaminase and hepatotoxicity. METHODS: 677 levodopa‐naïve patients with early stage Parkinson's disease (PD) were randomised to receive place...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMJ Group
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2117861/ https://ncbi.nlm.nih.gov/pubmed/17098835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2006.097154 |
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