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Fatigue in multiple sclerosis: an example of cytokine mediated sickness behaviour?

BACKGROUND: Fatigue is a major complaint of multiple sclerosis (MS) patients. However, little is known about its pathophysiological mechanisms. Evidence from chronic fatigue syndrome and studies on sickness behaviour suggest that immune and neuroendocrine factors may play a causative role in the dev...

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Detalhes bibliográficos
Main Authors: Heesen, C, Nawrath, L, Reich, C, Bauer, N, Schulz, K‐H, Gold, S M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117393/
https://ncbi.nlm.nih.gov/pubmed/16361589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2005.065805
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