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Identification of Novel High-Frequency DNA Methylation Changes in Breast Cancer

Recent data have revealed that epigenetic alterations, including DNA methylation and chromatin structure changes, are among the earliest molecular abnormalities to occur during tumorigenesis. The inherent thermodynamic stability of cytosine methylation and the apparent high specificity of the altera...

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Autors principals: Ordway, Jared M., Budiman, Muhammad A., Korshunova, Yulia, Maloney, Rebecca K., Bedell, Joseph A., Citek, Robert W., Bacher, Blaire, Peterson, Seth, Rohlfing, Tracy, Hall, Jacqueline, Brown, Robert, Lakey, Nathan, Doerge, Rebecca W., Martienssen, Robert A., Leon, Jorge, McPherson, John D., Jeddeloh, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117343/
https://ncbi.nlm.nih.gov/pubmed/18091988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001314
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