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Full-Exon Resequencing Reveals Toll-Like Receptor Variants Contribute to Human Susceptibility to Tuberculosis Disease

Tuberculosis (TB) is the leading cause of death worldwide due to an infectious agent. Data have accumulated over decades suggesting that variability in human susceptibility to TB disease has a genetic component. Toll-like receptors (TLRs) play a critical role in initiating the innate immune response...

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Autors principals: Ma, Xin, Liu, Yuhua, Gowen, Brian B., Graviss, Edward A., Clark, Andrew G., Musser, James M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117342/
https://ncbi.nlm.nih.gov/pubmed/18091991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001318
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