External validity of randomised controlled trials in asthma: to whom do the results of the trials apply?

BACKGROUND: Asthma is a heterogeneous disease with a wide range of clinical phenotypes, not all of which may be encompassed in the subjects included in randomised controlled trials (RCTs). This makes it difficult for clinicians to know to what extent the evidence derived from RCTs applies to a given...

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Main Authors: Travers, Justin, Marsh, Suzanne, Williams, Mathew, Weatherall, Mark, Caldwell, Brent, Shirtcliffe, Philippa, Aldington, Sarah, Beasley, Richard
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2007
Assuntos:
Asthma
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117157/
https://ncbi.nlm.nih.gov/pubmed/17105779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2006.066837
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