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Two cellular components, PrlA and SecB, that recognize different sequence determinants are required for efficient protein export.

We exploited the conditional-lethal phenotype of secB null mutations to demonstrate that SecB function was required for PrlA-mediated suppression of signal sequence mutations. The results of these experiments provide information about the functions performed and the sequence determinants recognized...

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Autors principals: Trun, N J, Stader, J, Lupas, A, Kumamoto, C, Silhavy, T J
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC211706/
https://ncbi.nlm.nih.gov/pubmed/3056926
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