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Immunoglobulin heavy chain and binding protein complexes are dissociated in vivo by light chain addition
Immunoglobulin heavy chain binding protein (BiP, GRP78) associates stably with the free, nonsecreted Ig heavy chains synthesized by Abelson virus transformed pre-B cell lines. In cells synthesizing both Ig heavy and light chains, the Ig subunits assemble rapidly and are secreted. Only incompletely a...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1990
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2116291/ https://ncbi.nlm.nih.gov/pubmed/2118144 |
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