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Exocytosis in mast cells by basic secretagogues: evidence for direct activation of GTP-binding proteins

Histamine release induced by the introduction of a nonhydrolyzable analogue of GTP, GTP-gamma-S, into ATP-permeabilized mast cells, is associated with phosphoinositide breakdown, as evidenced by the production of phosphatidic acid (PA) in a neomycin-sensitive process. The dependency of both PA forma...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2116270/
https://ncbi.nlm.nih.gov/pubmed/1697300
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