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The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

Receptor-bound urokinase-type plasminogen activator (uPA) remains associated to the surface of human monocytes for many hours. Monocytes induced to migrate in a chemotactic gradient of f-Met-Leu-Phe rapidly polarize their uPA receptors to the leading front of the cells. Receptor-bound enzyme can be...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2116194/
https://ncbi.nlm.nih.gov/pubmed/2166055
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