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Differential inhibition of nerve growth factor responses by purine analogues: correlation with inhibition of a nerve growth factor- activated protein kinase
Purine analogues were used in this study to dissect specific steps in the mechanism of action of nerve growth factor (NGF). Protein kinase N (PKN) is an NGF-activated serine protein kinase that is active in the presence of Mn++. The activity of PKN was inhibited in vitro by purine analogues, the mos...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1989
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2115883/ https://ncbi.nlm.nih.gov/pubmed/2553745 |
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