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A Dictyostelium discoideum mutant that missorts and oversecretes lysosomal enzyme precursors is defective in endocytosis

A mutant strain of Dictyostelium discoideum, HMW570, oversecretes several lysosomal enzyme activities during growth. Using a radiolabel pulse-chase protocol, we followed the synthesis and secretion of two of these enzymes, alpha-mannosidase and beta-glucosidase. A few hours into the chase period, HM...

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Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1989
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115801/
https://ncbi.nlm.nih.gov/pubmed/2507551
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