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Two trans-acting regulatory genes (vir and mod) control antigenic modulation in Bordetella pertussis.

Expression of virulence factors by Bordetella pertussis is altered by environmental signals (antigenic modulation) and is dependent on an activator encoded by a gene called vir. We have used TnphoA (Tn5 IS50L::phoA) gene fusions to define two sets of genes whose expression is either activated (vag l...

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Bibliografiske detaljer
Main Authors: Knapp, S, Mekalanos, J J
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC211571/
https://ncbi.nlm.nih.gov/pubmed/2903140
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