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Retrovirus-mediated expression of preprosomatostatin: posttranslational processing, intracellular storage, and secretion in GH3 pituitary cells

Somatostatin (SRIF) is a 14-amino acid peptide hormone that is synthesized as part of a larger precursor, preproSRIF, consisting of a signal peptide and a proregion of 80-90 amino acids. The mature hormone, which is located at the carboxyl terminus of the precursor, is preceded by a single pair of b...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115657/
https://ncbi.nlm.nih.gov/pubmed/2904447
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