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Simple assay for quantitation of Tn5 inversion events in Escherichia coli and use of the assay in determination of plasmid copy number.

In this report, we describe a simple method for measuring the frequency of sequence inversion in the transposable element Tn5 as a result of recombination across its duplicated IS50 elements. The structure of Tn5 was manipulated so that the neomycin phosphotransferase gene of the transposon would be...

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Hlavní autoři: Weber, P C, Levine, M, Glorioso, J C
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC211551/
https://ncbi.nlm.nih.gov/pubmed/2844732
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