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Availability of porphobilinogen controls appearance of porphobilinogen deaminase activity in Escherichia coli K-12.

A hemin-permeable hemB mutant had no 5-aminolevulinate dehydratase (ALA D) and extremely low porphobilinogen deaminase (PBG D) activity. When the structural gene for hemB was introduced into this strain on a single-copy plasmid, both activities were observed. When the mutant was grown on PBG, normal...

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Bibliographic Details
Main Authors: Umanoff, H, Russell, C S, Cosloy, S D
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC211550/
https://ncbi.nlm.nih.gov/pubmed/3049558
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