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Essential roles of the RNA polymerase I largest subunit and DNA topoisomerases in the formation of fission yeast nucleolus

A temperature-sensitive lethal mutant nuc1-632 of Schizosaccharomyces pombe shows marked reduction in macromolecular synthesis and a defective nuclear phenotype with an aberrant nucleolus, indicating a structural role of the nuc1+ gene product in nucleolar organization. We cloned the nuc1+ gene by t...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115420/
https://ncbi.nlm.nih.gov/pubmed/2537310
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