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New mammary epithelial and fibroblastic cell clones in coculture form structures competent to differentiate functionally

We have established and characterized a spontaneously immortalized, nontumorigenic mouse mammary cell line, designated IM-2. IM-2 cells synthesize large amounts of the milk protein beta-casein upon addition of lactogenic hormones. The induction of beta-casein occurs rapidly and does not require any...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115403/
https://ncbi.nlm.nih.gov/pubmed/2466037
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