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Activation of preexisting T cell clones by targeted interleukin 2 therapy

The induction of an immunological antitumor response capable of eradicating metastatic tumors is the ultimate goal of immunotherapy. We have recently shown that this can be achieved by interleukin 2 (IL-2) therapy directed to the tumor microenvironment by a recombinant antibody–IL-2 fusion protein....

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Autori principali: thor Straten, Per, Guldberg, Per, Seremet, Tina, Reisfeld, Ralph A., Zeuthen, Jesper, Becker, Jürgen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21154/
https://ncbi.nlm.nih.gov/pubmed/9671756
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