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Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen

Cells of the rat neuronal line, PC12, adhere well to substrates coated with laminin and type IV collagen, but attach poorly to fibronectin. Adhesion and neurite extension in response to these extracellular matrix proteins are inhibited by Fab fragments of an antiserum (anti- ECMR) that recognizes PC...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115278/
https://ncbi.nlm.nih.gov/pubmed/2843550
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