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An amino acid substitution in penicillin-binding protein 3 creates pointed polar caps in Escherichia coli.

The pbpB gene product penicillin-binding protein 3 (PBP3) of Escherichia coli is one of the major targets of beta-lactam antibiotics. At the permissive temperature, the temperature-sensitive pbpBr1 mutant, which was obtained after selection for increased resistance to cephalexin, shows a dramatic ch...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Taschner, P E, Ypenburg, N, Spratt, B G, Woldringh, C L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC211527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3049550/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.170.10.4828-4837.1988
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