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Polarized secretion of lysosomal enzymes: co-distribution of cation- independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathway

The osteoclast is a polarized cell which secretes large amounts of newly synthesized lysosomal enzymes into an apical extracellular lacuna where bone resorption takes place. Using immunocytochemical techniques, we have localized the cation-independent mannose-6-phosphate (Man6P) receptor and lysosom...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115156/
https://ncbi.nlm.nih.gov/pubmed/2968345
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