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Diverse effects of beta-tubulin mutations on microtubule formation and function

We have used in vitro mutagenesis and gene replacement to construct five new cold-sensitive mutations in TUB2, the sole gene encoding beta- tubulin in the yeast Saccharomyces cerevisiae. These and one previously isolated tub2 mutant display diverse phenotypes that have allowed us to define the funct...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2115142/
https://ncbi.nlm.nih.gov/pubmed/3290223
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