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A charged amino acid substitution within the transmembrane anchor of the Rous sarcoma virus envelope glycoprotein affects surface expression but not intracellular transport

Two point mutations were introduced by oligonucleotide-directed mutagenesis into the region of the Rous sarcoma virus envelope gene that encodes the hydrophobic transmembrane anchor of the receptor glycoprotein. Single-nucleotide substitutions ultimately converted a hydrophobic leucine, located cent...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114795/
https://ncbi.nlm.nih.gov/pubmed/2821009
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