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Translocation in yeast and mammalian cells: not all signal sequences are functionally equivalent

In Saccharomyces cerevisiae, nascent carboxypeptidase Y (CPY) is directed into the endoplasmic reticulum by an NH2-terminal signal peptide that is removed before the glycosylated protein is transported to the vacuole. In this paper, we show that this signal peptide does not function in mammalian cel...

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Détails bibliographiques
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1987
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114712/
https://ncbi.nlm.nih.gov/pubmed/3320059
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