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Lysosomal delivery of the major myelin glycoprotein in the absence of myelin assembly: posttranslational regulation of the level of expression by Schwann cells

The major myelin protein, P0, has been shown to have decreased levels of expression and altered oligosaccharide processing after the disruption of Schwann cell-axon interaction. We show here that lysosomal degradation of the glycoprotein shortly after its synthesis accounts for much of its decreased...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114530/
https://ncbi.nlm.nih.gov/pubmed/2434515
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