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Cleavage of membrane secretory component to soluble secretory component occurs on the cell surface of rat hepatocyte monolayers

Rat liver secretory component is synthesized as an integral membrane protein (mSC) and cleaved to an 80-kD soluble form (fSC) sometime during transcellular transport from the sinusoidal to the bile canalicular plasma membrane domain of hepatocytes. We have used 24-h monolayer cultures of rat hepatoc...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114513/
https://ncbi.nlm.nih.gov/pubmed/3294861
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