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The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole

The sensitivity of cultured human and hamster fibroblast cells to killing by the lysosomotropic detergent N-dodecylimidazole (C12-Im) was investigated as a function of cellular levels of general lysosomal hydrolase activity, and specifically of cysteine cathepsin activity. Fibroblasts from patients...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1987
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2114483/
https://ncbi.nlm.nih.gov/pubmed/3571330
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