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Pathways involved in targeting and secretion of a lysosomal enzyme in Dictyostelium discoideum

In Dictyostelium discoideum, the lysosomal enzyme alpha-mannosidase is first synthesized as an N-glycosylated precursor of Mr 140,000. After a 20-30-min lag period, up to 30% of the precursor molecules are rapidly secreted, whereas the rest remain cellular and are proteolytically processed (t 1/2 =...

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Détails bibliographiques
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1985
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113895/
https://ncbi.nlm.nih.gov/pubmed/3988807
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