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Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding

We have isolated chromosomes from Chinese hamster ovary cells arrested in mitosis with vinblastine and examined the interactions of their kinetochores with purified tubulin in vitro. The kinetochores nucleate microtubule (MT) growth with complex kinetics. After an initial lag phase, MTs are continuo...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1985
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113742/
https://ncbi.nlm.nih.gov/pubmed/4030893
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