Loading...
Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex
1- Deoxynojirimycin is a specific inhibitor of glucosidases I and II, the first enzymes that process N-linked oligosaccharides after their transfer to polypeptides in the rough endoplasmic reticulum. In a pulse- chase experiment, 1- deoxynojirimycin greatly reduced the rate of secretion of alpha 1-a...
Saved in:
| Format: | Artigo |
|---|---|
| Language: | Inglês |
| Published: |
The Rockefeller University Press
1984
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2113174/ https://ncbi.nlm.nih.gov/pubmed/6233287 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|