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1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells

The human-derived promyelocytic leukemia cell line, HL-60, is known to differentiate into mature myeloid cells in the presence of 1,25- dihydroxyvitamin D3 (1,25[OH]2D3). We investigated differentiation by monitoring 1,25(OH)2D3-exposed HL-60 cells for phagocytic activity, ability to reduce nitroblu...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1984
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113084/
https://ncbi.nlm.nih.gov/pubmed/6319426
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