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Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics

We have used biochemical and morphological techniques to demonstrate that hepatocytes in the perfused liver bind, internalize, and degrade substantial amounts of murine epidermal growth factor (EGF) via a receptor-mediated process. Before ligand exposure, about 300,000 high- affinity receptors were...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1984
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2113050/
https://ncbi.nlm.nih.gov/pubmed/6327725
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