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Excitation, adaption, and deadaptation of the cAMP-mediated cGMP Response in dictyostelium discoideum

Extracellular cAMP induces chemotaxis and cell aggregation in dictyostelium discoideum cells. cAMP added to a cell suspension is rapidly hydrolyzed (half-life of 10 s) and induces a rapid increase of intracellular cGMP levels, which reach a peak at 10 s and recover prestimulated levels at about 30 s...

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Detalhes bibliográficos
Main Authors: Van Haaster, PJM, Van Der Heijden, PR
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2112281/
https://ncbi.nlm.nih.gov/pubmed/6300135
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