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Intracellular distribution and degradation of immunoglobulin G and immunoglobulin G fragments injected into HeLa cells
Intact rabbit immunoglobulin G molecules (IgGs) and their papain or pepsin fragments were radio-iodinated and injected into HeLa cells. Whole IgGs, Fab2, and Fc fragments were degraded with half-lives of 60- 90 h, whereas half-lives of Fab fragments were 110 h. These results indicate that proteolyti...
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| Формат: | Artigo |
|---|---|
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
1983
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2112279/ https://ncbi.nlm.nih.gov/pubmed/6403551 |
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