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Intracellular distribution and degradation of immunoglobulin G and immunoglobulin G fragments injected into HeLa cells

Intact rabbit immunoglobulin G molecules (IgGs) and their papain or pepsin fragments were radio-iodinated and injected into HeLa cells. Whole IgGs, Fab2, and Fc fragments were degraded with half-lives of 60- 90 h, whereas half-lives of Fab fragments were 110 h. These results indicate that proteolyti...

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Dades bibliogràfiques
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2112279/
https://ncbi.nlm.nih.gov/pubmed/6403551
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