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Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site- specific arrest of chain elongation that is released by microsomal membranes

The previously observed (Walter, et al. 1981 J. Cell Biol. 91:545-550) inhibitory effect of SRP selectively on the cell-free translation of mRNA for secretory protein (preprolactin) was shown here to be caused by a signal sequence-induced and site-specific arrest in polypeptide chain elongation. The...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111983/
https://ncbi.nlm.nih.gov/pubmed/7309797
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