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Gating modifier toxins reveal a conserved structural motif in voltage-gated Ca(2+) and K(+) channels

Protein toxins from venomous animals exhibit remarkably specific and selective interactions with a wide variety of ion channels. Hanatoxin and grammotoxin are two related protein toxins found in the venom of the Chilean Rose Tarantula, Phrixotrichus spatulata. Hanatoxin inhibits voltage-gated K(+) c...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Li-Smerin, Yingying, Swartz, Kenton J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21119/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671721/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.15.8585
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