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Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells

When a clonal line of rat pheochromocytoma (PC12) was exposed to beta- nerve growth factor (beta NGF), N6, O2-dibutyryl adenosine 3':5' cyclic monophosphate (Bt2cAMP), or a combination of the two, 10, 26, or 70% of the cell clumps, respectively, displayed neurites after 1.d. Increases in t...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1981
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111685/
https://ncbi.nlm.nih.gov/pubmed/6265462
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