Llwytho...

Suppression of NF-κB-mediated β-defensin gene expression in the mammalian airway by the Bordetella type III secretion system

Expression of innate immune genes such as β-defensins is induced in airway epithelium by bacterial components via activation of NF-κB. We show here that live Gram-negative bacteria can similarly stimulate this pathway, resulting in upregulation of the β-defensin tracheal antimicrobial peptide (TAP)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Legarda, Diana, Klein-Patel, Marcia E., Yim, Sunghan, Yuk, Ming H., Diamond, Gill
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111170/
https://ncbi.nlm.nih.gov/pubmed/15760449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2004.00473.x
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