The Role of Macrophage Migration Inhibitory Factor in the Cascade of Events Leading to Reperfusion-Induced Inflammatory Injury and Lethality

Ischemia and reperfusion (I/R) injury is associated with a systemic inflammatory response, characterized by intense tumor necrosis factor (TNF)-α production and TNF-α-dependent tissue injury. Macrophage migration inhibitory factor (MIF) is a potent proinflammatory cytokine that may induce TNF-α rele...

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Detalhes bibliográficos
Main Authors: Amaral, Flávio A., Fagundes, Caio T., Guabiraba, Rodrigo, Vieira, Angélica T., Souza, Adriano L.S., Russo, Remo C., Soares, Milena P.B., Teixeira, Mauro M., Souza, Danielle G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111111/
https://ncbi.nlm.nih.gov/pubmed/18055556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060642
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