Myeloperoxidase Is Critically Involved in the Induction of Organ Damage after Renal Ischemia Reperfusion

In this study the role of myeloperoxidase (MPO) in a murine (C57BL/6) model of ischemia and reperfusion (I/R)-induced renal failure was investigated. The renal function after I/R was analyzed in MPO-deficient (Mpo(−/−)) mice and compared with wild-type (WT) controls. A significant reduction in renal...

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Detalhes bibliográficos
Main Authors: Matthijsen, Robert A., Huugen, Dennis, Hoebers, Nicole T., de Vries, Bart, Peutz-Kootstra, Carine J., Aratani, Yasuaki, Daha, Mohamed R., Tervaert, Jan Willem Cohen, Buurman, Wim A., Heeringa, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111099/
https://ncbi.nlm.nih.gov/pubmed/18055546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.070184
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