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Effect of substitution of glycine for arginine at position 146 of the A1 subunit on biological activity of Escherichia coli heat-labile enterotoxin.

The ADP-ribosyltransferase activity of polypeptide A1 of cholera toxin and that of Escherichia coli heat-labile enterotoxin (LT) are primarily responsible for the toxic activities of these toxins. Since the amino acid sequences of the two A1 polypeptides are very similar, their functional mechanisms...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Okamoto, K, Miyama, A, Tsuji, T, Honda, T, Miwatani, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC211108/
https://ncbi.nlm.nih.gov/pubmed/3129402
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