3,N(4)-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase
Exocyclic DNA adducts are generated in cellular DNA by various industrial pollutants such as the carcinogen vinyl chloride and by endogenous products of lipid peroxidation. The etheno derivatives of purine and pyrimidine bases 3,N(4)-ethenocytosine (ɛC), 1,N(6)-ethenoadenine (ɛA), N(2),3-ethenoguani...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.15.8508 |
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