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Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

The PC12 clone is a noradrenergic cell line derived from a rat pheochromocytoma. In culture medium containing horse serum, PC12 cells undergo mitosis; when nerve growth factor (NGF) is included in the medium, the cells cease multiplication and extend neuritis. It is shown here: (a) that PC12 cells a...

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Bibliographic Details
Main Author: Greene, LA
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1978
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2110184/
https://ncbi.nlm.nih.gov/pubmed/701359
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