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Effects of 5-bromodeoxyuridine on the ACTH-dependent mitochondrial biogenesis in cortical cells of fetal rat adrenals in tissue culture

Cortical cells of fetal rat adrenals in tissue culture were treated with 5-bromodeoxyuridine (BrdU) during their proliferative phase and during ACTH stimulation when nuclear DNA synthesis has almost ceased. Pretreatment with 0.5 mug/ml/day of BrdU inhibited the ACTH-induced differentiation of cortic...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1976
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2109781/
https://ncbi.nlm.nih.gov/pubmed/186465
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